Unintended Mutations

Mutations can affect the functioning of many genes, with unknown consequences for biochemical composition and function. In the case of plants, this can result in altered levels of allergens and toxins.

Most of the DNA damage described below is outside the control of genetic engineers, as it is a consequence of the cell’s DNA repair machinery (after the gene-editing tool creates cuts in the genome.) Therefore, future improvements in targeting a desired location in the genome will not be the solution.

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